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SEQUENCE SLIDER: expanding polyalanine fragments for phasing with multiple side-chain hypotheses
Fragment-based molecular-replacement methods can solve a macromolecular structure quasi-ab initio. ARCIMBOLDO, using a common secondary-structure or tertiary-structure template or a library of folds, locates these with Phaser and reveals the rest of the structure by density modification and autotrac...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057211/ https://www.ncbi.nlm.nih.gov/pubmed/32133987 http://dx.doi.org/10.1107/S2059798320000339 |