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SEQUENCE SLIDER: expanding polyalanine fragments for phasing with multiple side-chain hypotheses

Fragment-based molecular-replacement methods can solve a macromolecular structure quasi-ab initio. ARCIMBOLDO, using a common secondary-structure or tertiary-structure template or a library of folds, locates these with Phaser and reveals the rest of the structure by density modification and autotrac...

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Detalles Bibliográficos
Autores principales: Borges, Rafael Junqueira, Meindl, Kathrin, Triviño, Josep, Sammito, Massimo, Medina, Ana, Millán, Claudia, Alcorlo, Martin, Hermoso, Juan A., Fontes, Marcos Roberto de Mattos, Usón, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057211/
https://www.ncbi.nlm.nih.gov/pubmed/32133987
http://dx.doi.org/10.1107/S2059798320000339