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Bone marrow mesenchymal stem cells combined with ultra-purified alginate gel as a regenerative therapeutic strategy after discectomy for degenerated intervertebral discs

BACKGROUND: Because the regenerative ability of intervertebral discs (IVDs) is restricted, defects caused by discectomy may induce insufficient tissue repair leading to further IVD degeneration. An acellular bioresorbable biomaterial based on ultra-purified alginate (UPAL) gel was developed to fill...

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Detalles Bibliográficos
Autores principales: Ukeba, Daisuke, Sudo, Hideki, Tsujimoto, Takeru, Ura, Katsuro, Yamada, Katsuhisa, Iwasaki, Norimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057222/
https://www.ncbi.nlm.nih.gov/pubmed/32143180
http://dx.doi.org/10.1016/j.ebiom.2020.102698