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Bone gain following loading is site-specifically enhanced by prior and concurrent disuse in aged male mice

The primary aim of osteoanabolic therapies is to strategically increase bone mass in skeletal regions likely to experience high strains. In the young healthy skeleton, this is primarily achieved by bone's adaptation to loading. This adaptation appears to fail with age, resulting in osteoporosis...

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Detalles Bibliográficos
Autores principales: Galea, Gabriel L., Delisser, Peter J., Meakin, Lee, Price, Joanna S., Windahl, Sara H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057260/
https://www.ncbi.nlm.nih.gov/pubmed/31991251
http://dx.doi.org/10.1016/j.bone.2020.115255