Early-life inhalant allergen exposure, filaggrin genotype, and the development of sensitization from infancy to adolescence

BACKGROUND: We hypothesized that filaggrin (FLG) loss-of-function mutations modify the effect of allergen exposure on the development of allergic sensitization. OBJECTIVE: We sought to determine whether early-life exposure to inhalant allergens increases the risk of specific sensitization and whethe...

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Detalles Bibliográficos
Autores principales: Simpson, Angela, Brough, Helen A., Haider, Sadia, Belgrave, Danielle, Murray, Clare S., Custovic, Adnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mosby 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057264/
https://www.ncbi.nlm.nih.gov/pubmed/31629803
http://dx.doi.org/10.1016/j.jaci.2019.08.041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057264/
https://www.ncbi.nlm.nih.gov/pubmed/31629803
http://dx.doi.org/10.1016/j.jaci.2019.08.041

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