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Distinct Polymorphisms in HLA Class I Molecules Govern Their Susceptibility to Peptide Editing by TAPBPR

Understanding how peptide selection is controlled on different major histocompatibility complex class I (MHC I) molecules is pivotal for determining how variations in these proteins influence our predisposition to infectious diseases, cancer, and autoinflammatory conditions. Although the intracellul...

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Detalles Bibliográficos
Autores principales: Ilca, F. Tudor, Drexhage, Linnea Z., Brewin, Gemma, Peacock, Sarah, Boyle, Louise H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057265/
https://www.ncbi.nlm.nih.gov/pubmed/31693900
http://dx.doi.org/10.1016/j.celrep.2019.09.074