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Distinct Polymorphisms in HLA Class I Molecules Govern Their Susceptibility to Peptide Editing by TAPBPR
Understanding how peptide selection is controlled on different major histocompatibility complex class I (MHC I) molecules is pivotal for determining how variations in these proteins influence our predisposition to infectious diseases, cancer, and autoinflammatory conditions. Although the intracellul...
Autores principales: | Ilca, F. Tudor, Drexhage, Linnea Z., Brewin, Gemma, Peacock, Sarah, Boyle, Louise H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057265/ https://www.ncbi.nlm.nih.gov/pubmed/31693900 http://dx.doi.org/10.1016/j.celrep.2019.09.074 |
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