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The Secret Life of Chromosome Loops upon DNA Double-Strand Break
DNA double-strand breaks (DSBs) are harmful lesions that severely challenge genomic integrity, and recent evidence suggests that DSBs occur more frequently on the genome than previously thought. These lesions activate a complex and multilayered response called the DNA damage response, which allows t...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057266/ https://www.ncbi.nlm.nih.gov/pubmed/31401119 http://dx.doi.org/10.1016/j.jmb.2019.07.036 |