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The Secret Life of Chromosome Loops upon DNA Double-Strand Break

DNA double-strand breaks (DSBs) are harmful lesions that severely challenge genomic integrity, and recent evidence suggests that DSBs occur more frequently on the genome than previously thought. These lesions activate a complex and multilayered response called the DNA damage response, which allows t...

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Detalles Bibliográficos
Autores principales: Arnould, Coline, Legube, Gaëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057266/
https://www.ncbi.nlm.nih.gov/pubmed/31401119
http://dx.doi.org/10.1016/j.jmb.2019.07.036