Specific Contributions of Cohesin-SA1 and Cohesin-SA2 to TADs and Polycomb Domains in Embryonic Stem Cells

Cohesin exists in two variants carrying either STAG/SA1 or SA2. Here we have addressed their specific contributions to the unique spatial organization of the mouse embryonic stem cell genome, which ensures super-enhancer-dependent transcription of pluripotency factors and repression of lineage-speci...

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Detalles Bibliográficos
Autores principales: Cuadrado, Ana, Giménez-Llorente, Daniel, Kojic, Aleksandar, Rodríguez-Corsino, Miriam, Cuartero, Yasmina, Martín-Serrano, Guillermo, Gómez-López, Gonzalo, Marti-Renom, Marc A., Losada, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057268/
https://www.ncbi.nlm.nih.gov/pubmed/31216471
http://dx.doi.org/10.1016/j.celrep.2019.05.078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057268/
https://www.ncbi.nlm.nih.gov/pubmed/31216471
http://dx.doi.org/10.1016/j.celrep.2019.05.078

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