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Investigating Conformational Dynamics of Lewis Y Oligosaccharides and Elucidating Blood Group Dependency of Cholera Using Molecular Dynamics

[Image: see text] Cholera is caused by Vibrio cholerae and is an example of a blood-group-dependent disease. Recent studies suggest that the receptor-binding B subunit of the cholera toxin (CT) binds histo–blood group antigens at a secondary binding site. Herein, we studied the conformational dynami...

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Detalles Bibliográficos
Autores principales: Roy, Rajarshi, Ghosh, Biplab, Kar, Parimal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057322/
https://www.ncbi.nlm.nih.gov/pubmed/32149220
http://dx.doi.org/10.1021/acsomega.9b03398