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OffScan: a universal and fast CRISPR off-target sites detection tool

BACKGROUND: The Type II clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated proteins (Cas) is a powerful genome editing technology, which is more and more popular in gene function analysis. In CRISPR/Cas, RNA guides Cas nuclease to the target site to perform DNA...

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Detalles Bibliográficos
Autores principales: Cui, Yingbo, Liao, Xiangke, Peng, Shaoliang, Tang, Tao, Huang, Chun, Yang, Canqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057453/
https://www.ncbi.nlm.nih.gov/pubmed/32138651
http://dx.doi.org/10.1186/s12864-019-6241-9