Cargando…

OffScan: a universal and fast CRISPR off-target sites detection tool

BACKGROUND: The Type II clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated proteins (Cas) is a powerful genome editing technology, which is more and more popular in gene function analysis. In CRISPR/Cas, RNA guides Cas nuclease to the target site to perform DNA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cui, Yingbo, Liao, Xiangke, Peng, Shaoliang, Tang, Tao, Huang, Chun, Yang, Canqun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057453/ https://www.ncbi.nlm.nih.gov/pubmed/32138651 http://dx.doi.org/10.1186/s12864-019-6241-9

Ejemplares similares

VISPR-online: a web-based interactive tool to visualize CRISPR screening experiments
por: Cui, Yingbo, et al.
Publicado: (2021)

A Review of Parallel Implementations for the Smith–Waterman Algorithm
por: Xia, Zeyu, et al.
Publicado: (2021)

P-Hint-Hunt: a deep parallelized whole genome DNA methylation detection tool
por: Peng, Shaoliang, et al.
Publicado: (2017)

OffRisk: a docker image for annotating CRISPR off-target sites in the human genome
por: Barkai, Gil-ad, et al.
Publicado: (2023)

JACKIE: Fast Enumeration of Genome-Wide Single- and Multicopy CRISPR Target Sites and Their Off-Target Numbers
por: Zhu, Jacqueline Jufen, et al.
Publicado: (2022)

COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites
por: Cradick, Thomas J, et al.
Publicado: (2014)

CRISPRon/off: CRISPR/Cas9 on- and off-target gRNA design
por: Anthon, Christian, et al.
Publicado: (2022)

CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites
por: Naito, Yuki, et al.
Publicado: (2015)

CRISPR/Cas Systems in Genome Editing: Methodologies and Tools for sgRNA Design, Off‐Target Evaluation, and Strategies to Mitigate Off‐Target Effects
por: Manghwar, Hakim, et al.
Publicado: (2020)

Scan of Working Diamond at Injection with RF off
por: Cornacchia, M, et al.
Publicado: (1976)

“Off-Spotter”: very fast and exhaustive enumeration of genomic lookalikes for designing CRISPR/Cas guide RNAs
por: Pliatsika, Venetia, et al.
Publicado: (2015)

Evaluation and Reduction of CRISPR Off-Target Cleavage Events
por: Vakulskas, Christopher A., et al.
Publicado: (2019)

Supramolecular CRISPR-OFF switches with host–guest chemistry
por: Xiong, Wei, et al.
Publicado: (2022)

CRISPR nuclease off-target activity and mitigation strategies
por: Wienert, Beeke, et al.
Publicado: (2022)

Current Bioinformatics Tools to Optimize CRISPR/Cas9 Experiments to Reduce Off-Target Effects
por: Naeem, Muhammad, et al.
Publicado: (2023)

qEva-CRISPR: a method for quantitative evaluation of CRISPR/Cas-mediated genome editing in target and off-target sites
por: Dabrowska, Magdalena, et al.
Publicado: (2018)

Massively targeted evaluation of therapeutic CRISPR off-targets in cells
por: Pan, Xiaoguang, et al.
Publicado: (2022)

CRISPR-offinder: a CRISPR guide RNA design and off-target searching tool for user-defined protospacer adjacent motif
por: Zhao, Changzhi, et al.
Publicado: (2017)

CERN: Fast trigger logic off the shelf
Publicado: (1981)

Specificity profiling of CRISPR system reveals greatly enhanced off-target gene editing
por: Wang, Yao, et al.
Publicado: (2020)

CRISPR-FRT targets shared sites in a knock-out collection for off-the-shelf genome editing
por: Swings, Toon, et al.
Publicado: (2018)

Universality of the off-equilibrium critical fragmentation
por: Botet, R, et al.
Publicado: (1998)

Corrigendum: CRISPR nuclease off-target activity and mitigation strategies
por: Wienert, Beeke, et al.
Publicado: (2023)

Systematic identification of CRISPR off-target effects by CROss-seq
por: Li, Yan, et al.
Publicado: (2022)

Off-target effects in CRISPR/Cas9 gene editing
por: Guo, Congting, et al.
Publicado: (2023)

Off-target predictions in CRISPR-Cas9 gene editing using deep learning
por: Lin, Jiecong, et al.
Publicado: (2018)

crisprSQL: a novel database platform for CRISPR/Cas off-target cleavage assays
por: Störtz, Florian, et al.
Publicado: (2020)

Planck satellite takes off to chart the universe
Publicado: (2009)

LHCb Off-site HLT Farm Demonstration
por: Neufeld, Niko, et al.
Publicado: (2012)

Health technology assessment: Off-site sterilization
por: Dehnavieh, Reza, et al.
Publicado: (2016)

On-site or off-site treatment of medical waste: a challenge
por: Taghipour, Hassan, et al.
Publicado: (2014)

Off-target Effects in CRISPR/Cas9-mediated Genome Engineering
por: Zhang, Xiao-Hui, et al.
Publicado: (2015)

In vivo CRISPR editing with no detectable genome-wide off-target mutations
por: Akcakaya, Pinar, et al.
Publicado: (2018)

Benchmarking and integrating genome-wide CRISPR off-target detection and prediction
por: Yan, Jifang, et al.
Publicado: (2020)

Improving the sensitivity of in vivo CRISPR off-target detection with DISCOVER-Seq+
por: Zou, Roger S., et al.
Publicado: (2023)

A massively parallel approach for assessing CRISPR off-targets in vitro
por: Huang, Shisheng, et al.
Publicado: (2023)

Improving Ultra-Low Temperature Preservation Technologies of Soybean Pollen for Off-Season and Off-Site Hybridization
por: Jia, Hongchang, et al.
Publicado: (2022)

Combining Comprehensive Analysis of Off-Site Lambda Phage Integration with a CRISPR-Based Means of Characterizing Downstream Physiology
por: Tanouchi, Yu, et al.
Publicado: (2017)

CRISPR GUARD protects off-target sites from Cas9 nuclease activity using short guide RNAs
por: Coelho, Matthew A., et al.
Publicado: (2020)

CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations
por: Höijer, Ida, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_lauemvtn8e6qdr4bcelejjq1os