Interferon gamma inhibits CXCL8–CXCR2 axis mediated tumor-associated macrophages tumor trafficking and enhances anti-PD1 efficacy in pancreatic cancer

BACKGROUND: Pancreatic cancer (PC) is a common malignancy of the digestive system and is characterized by poor prognosis and early metastasis. Tumor immune escape plays an important role in PC progression. Programmed death 1 (PD1) blockade therapy is a promising treatment for patients with PC, but i...

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Detalles Bibliográficos
Autores principales: Zhang, Mingjie, Huang, Lifeng, Ding, Guoping, Huang, Huilian, Cao, Guoliang, Sun, Xu, Lou, Neng, Wei, Qiang, Shen, Tao, Xu, Xiaodong, Cao, Liping, Yan, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057481/
https://www.ncbi.nlm.nih.gov/pubmed/32051287
http://dx.doi.org/10.1136/jitc-2019-000308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057481/
https://www.ncbi.nlm.nih.gov/pubmed/32051287
http://dx.doi.org/10.1136/jitc-2019-000308

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