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Breast cancer pathogenesis is linked to the intra-tumoral estrogen sulfotransferase (hSULT1E1) expressions regulated by cellular redox dependent Nrf-2/NFκβ interplay

BACKGROUND: Estrogen sulfotransferase catalyzes conjugation of sulfuryl-group to estradiol/estrone and regulates E2 availability/activity via estrogen-receptor or non-receptor mediated pathways. Sulfoconjugated estrogen fails to bind estrogen-receptor (ER). High estrogen is a known carcinogen in pos...

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Detalles Bibliográficos
Autores principales:	Nazmeen, Aarifa, Chen, Guangping, Ghosh, Tamal Kanti, Maiti, Smarajit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057506/ https://www.ncbi.nlm.nih.gov/pubmed/32158360 http://dx.doi.org/10.1186/s12935-020-1153-y

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