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Non-thermal histotripsy tumor ablation promotes abscopal immune responses that enhance cancer immunotherapy

BACKGROUND: Developing the ability to use tumor-directed therapies to trigger potentially therapeutic immune responses against cancer antigens remains a high priority for cancer immunotherapy. We hypothesized that histotripsy, a novel non-invasive, non-thermal ablation modality that uses ultrasound-...

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Detalles Bibliográficos
Autores principales: Qu, Shibin, Worlikar, Tejaswi, Felsted, Amy E, Ganguly, Anutosh, Beems, Megan V, Hubbard, Ryan, Pepple, Ashley L, Kevelin, Alicia A, Garavaglia, Hannah, Dib, Joe, Toma, Mariam, Huang, Hai, Tsung, Allan, Xu, Zhen, Cho, Clifford Suhyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057529/
https://www.ncbi.nlm.nih.gov/pubmed/31940590
http://dx.doi.org/10.1136/jitc-2019-000200