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Betaine attenuates LPS-induced downregulation of Occludin and Claudin-1 and restores intestinal barrier function

BACKGROUND: The intestinal epithelial barrier, which works as the first line of defense between the luminal environment and the host, once destroyed, it will cause serious inflammation or other intestinal diseases. Tight junctions (TJs) play a vital role to maintain the integrity of the epithelial b...

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Detalles Bibliográficos
Autores principales: Wu, Jingtao, He, Caimei, Bu, Jie, Luo, Yue, Yang, Shuyuan, Ye, Chengyan, Yu, Silei, He, Binsheng, Yin, Yulong, Yang, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057534/
https://www.ncbi.nlm.nih.gov/pubmed/32131830
http://dx.doi.org/10.1186/s12917-020-02298-3