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Betaine attenuates LPS-induced downregulation of Occludin and Claudin-1 and restores intestinal barrier function
BACKGROUND: The intestinal epithelial barrier, which works as the first line of defense between the luminal environment and the host, once destroyed, it will cause serious inflammation or other intestinal diseases. Tight junctions (TJs) play a vital role to maintain the integrity of the epithelial b...
Autores principales: | Wu, Jingtao, He, Caimei, Bu, Jie, Luo, Yue, Yang, Shuyuan, Ye, Chengyan, Yu, Silei, He, Binsheng, Yin, Yulong, Yang, Xiaoping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057534/ https://www.ncbi.nlm.nih.gov/pubmed/32131830 http://dx.doi.org/10.1186/s12917-020-02298-3 |
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