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Association of CYP2A6 gene deletion with cancers in Japanese elderly: an autopsy study

BACKGROUND: CYP2A6 is an enzyme involved in oxidation of a number of environmental chemicals, including nicotine, pro-carcinogenic nitrosamines and polycyclic aromatic hydrocarbons (PAHs). The whole gene deletion of CYP2A6 (CYP2A6*4) is prevalent in East Asian population. Whether or not CYP2A6*4 ass...

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Detalles Bibliográficos
Autores principales: Abudushataer, Maidina, Sato, Noriko, Mieno, Makiko, Sawabe, Motoji, Muramatsu, Masaaki, Arai, Tomio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057549/
https://www.ncbi.nlm.nih.gov/pubmed/32131765
http://dx.doi.org/10.1186/s12885-020-6663-4