Efficacy, immunogenicity, and safety of IC43 recombinant Pseudomonas aeruginosa vaccine in mechanically ventilated intensive care patients—a randomized clinical trial

BACKGROUND: Pseudomonas aeruginosa infections are a serious threat in intensive care units (ICUs). The aim of this confirmatory, randomized, multicenter, placebo-controlled, double-blind, phase 2/3 study was to assess the efficacy, immunogenicity, and safety of IC43 recombinant Pseudomonas aeruginos...

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Detalles Bibliográficos
Autores principales: Adlbrecht, Christopher, Wurm, Raphael, Depuydt, Pieter, Spapen, Herbert, Lorente, Jose A., Staudinger, Thomas, Creteur, Jacques, Zauner, Christian, Meier-Hellmann, Andreas, Eller, Philipp, Laenen, Margot Vander, Molnár, Zsolt, Várkonyi, István, Schaaf, Bernhard, Héjja, Mária, Šrámek, Vladimír, Schneider, Hauke, Kanesa-thasan, Niranjan, Eder-Lingelbach, Susanne, Klingler, Anton, Dubischar, Katrin, Wressnigg, Nina, Rello, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057595/
https://www.ncbi.nlm.nih.gov/pubmed/32131866
http://dx.doi.org/10.1186/s13054-020-2792-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057595/
https://www.ncbi.nlm.nih.gov/pubmed/32131866
http://dx.doi.org/10.1186/s13054-020-2792-z

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