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Germline BRCA, chemotherapy response scores, and survival in the neoadjuvant treatment of ovarian cancer

BACKGROUND: To analyze the effects of BRCA1/2 mutations on chemotherapy response scores (CRS) and survival in a cohort of patients with advanced-stage ovarian cancer who were treated with neoadjuvant chemotherapy (NAC) followed by interval debulking surgery (IDS). METHODS: We retrospectively reviewe...

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Detalles Bibliográficos
Autores principales: Lee, Yong Jae, Kim, Hyun-Soo, Rim, John Hoon, Lee, Jung-Yun, Nam, Eun Ji, Kim, Sang Wun, Kim, Sunghoon, Kim, Young Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057666/
https://www.ncbi.nlm.nih.gov/pubmed/32131779
http://dx.doi.org/10.1186/s12885-020-6688-8