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Optimal Mutant Model of Human S100A3 Protein Citrullinated at Arg51 by Peptidylarginine Deiminase Type III and Its Solution Structural Properties

[Image: see text] S100A3 protein, a member of the EF-hand-type Ca(2+)-binding S100 protein family, undergoes a Ca(2+)-/Zn(2+)-induced structural change to a tetrameric state upon specific citrullination of R51 in human hair cuticular cells. To elucidate the underlying mechanism, we prepared recombin...

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Detalles Bibliográficos
Autores principales: Ite, Kenji, Yonezawa, Kento, Kitanishi, Kenichi, Shimizu, Nobutaka, Unno, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057681/
https://www.ncbi.nlm.nih.gov/pubmed/32149230
http://dx.doi.org/10.1021/acsomega.9b03618