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Therapeutic Potentials of Inhibition of Jumonji C Domain-containing Demethylases in Acute Myeloid Leukemia

OBJECTIVE: Acute myeloid leukemia (AML) is a complex disease affected by both genetic and epigenetic factors. Histone methylation and demethylation are types of epigenetic modification in chromatin remodeling and gene expression. Abnormal expression of histone demethylases is indicated in many types...

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Detalles Bibliográficos
Autores principales: Koca, Duygu, Hastar, Nurcan, Engür, Selin, Kiraz, Yağmur, Ulu, Gizem Tuğçe, Çekdemir, Demet, Baran, Yusuf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057756/
https://www.ncbi.nlm.nih.gov/pubmed/31833715
http://dx.doi.org/10.4274/tjh.galenos.2019.2019.0083