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Exosomes from adipose-derived stem cells promote chondrogenesis and suppress inflammation by upregulating miR-145 and miR-221

Osteoarthritis (OA) is one of the most prevalent joint disorders globally. Patients suffering from OA are often obese and adiposity is linked to chronic inflammation. In the present study, the potential of using exosomes isolated from adipose-derived stem cells (ADSCs) as a therapeutic tool for redu...

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Detalles Bibliográficos
Autores principales: Zhao, Chen, Chen, Jin-Yang, Peng, Wen-Ming, Yuan, Bo, Bi, Qing, Xu, You-Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057766/
https://www.ncbi.nlm.nih.gov/pubmed/32319611
http://dx.doi.org/10.3892/mmr.2020.10982