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FOXO3a is stabilized by USP18-mediated de-ISGylation and inhibits TGF-β1-induced fibronectin expression

FOXO3a belongs to a family of transcription factors characterized by a conserved forkhead box DNA-binding domain. It has been known to regulate various cellular processes including cell proliferation, apoptosis and differentiation. Post-translational modifications of FOXO3a and their roles in the re...

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Detalles Bibliográficos
Autores principales: Wang, Ban, Li, Yanhui, Wang, Heather, Zhao, Jing, Zhao, Yutong, Liu, Zhonghui, Ma, Haichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057795/
https://www.ncbi.nlm.nih.gov/pubmed/31874933
http://dx.doi.org/10.1136/jim-2019-001145