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Knockdown of MMP-1 inhibits the progression of colorectal cancer by suppressing the PI3K/Akt/c-myc signaling pathway and EMT

The present study aimed to investigate the role of matrix metalloproteinase-1 (MMP-1) in the development of colorectal cancer and reveal the mechanism underlying this progression. Bioinformatics methods and a public dataset were first used to analyze MMP-1 gene expression in a public dataset. MMP-1...

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Detalles Bibliográficos
Autores principales: Wang, Kai, Zheng, Jianbao, Yu, Junhui, Wu, Yunhua, Guo, Jing, Xu, Zhengshui, Sun, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057971/
https://www.ncbi.nlm.nih.gov/pubmed/32323782
http://dx.doi.org/10.3892/or.2020.7490