Recapitulating T cell infiltration in 3D psoriatic skin models for patient-specific drug testing

Drug screening studies for inflammatory skin diseases are currently performed using model systems that only partially recapitulate human diseased skin. Here, we developed a new strategy to incorporate T cells into human 3D skin constructs (HSCs), which enabled us to closely monitor and quantitate T...

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Detalles Bibliográficos
Autores principales: Shin, Jung U, Abaci, Hasan E., Herron, Lauren, Guo, Zongyou, Sallee, Brigitte, Pappalardo, Alberto, Jackow, Joanna, Wang, Eddy Hsi Chun, Doucet, Yanne, Christiano, Angela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057979/
https://www.ncbi.nlm.nih.gov/pubmed/32139717
http://dx.doi.org/10.1038/s41598-020-60275-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057979/
https://www.ncbi.nlm.nih.gov/pubmed/32139717
http://dx.doi.org/10.1038/s41598-020-60275-0

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