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Recapitulating T cell infiltration in 3D psoriatic skin models for patient-specific drug testing
Drug screening studies for inflammatory skin diseases are currently performed using model systems that only partially recapitulate human diseased skin. Here, we developed a new strategy to incorporate T cells into human 3D skin constructs (HSCs), which enabled us to closely monitor and quantitate T...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057979/ https://www.ncbi.nlm.nih.gov/pubmed/32139717 http://dx.doi.org/10.1038/s41598-020-60275-0 |