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Human glutaredoxin-1 can transfer copper to isolated metal binding domains of the P(1B)-type ATPase, ATP7B
Intracellular copper (Cu) in eukaryotic organisms is regulated by homeostatic systems, which rely on the activities of soluble metallochaperones that participate in Cu exchange through highly tuned protein-protein interactions. Recently, the human enzyme glutaredoxin-1 (hGrx1) has been shown to poss...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057996/ https://www.ncbi.nlm.nih.gov/pubmed/32139726 http://dx.doi.org/10.1038/s41598-020-60953-z |