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TRPC6-dependent Ca(2+) signaling mediates airway inflammation in response to oxidative stress via ERK pathway

Ozone (O(3)) plays an extremely important role in airway inflammation by generating reactive oxygen species (ROS) including hydrogen peroxide, then promoting redox actions and causing oxidative stress. Evidences indicate that TRPC6 (canonical transient receptor potential channel 6) is a redox-regula...

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Detalles Bibliográficos
Autores principales: Chen, Qingzi, Zhou, Yubo, Zhou, Lifen, Fu, Zhaodi, Yang, Chuntao, Zhao, Lei, Li, Shuni, Chen, Yan, Wu, Yousen, Ling, Zhenwei, Wang, Yufeng, Huang, Jianrong, Li, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058000/
https://www.ncbi.nlm.nih.gov/pubmed/32139669
http://dx.doi.org/10.1038/s41419-020-2360-0