Photoinduced damage of AsLOV2 domain is accompanied by increased singlet oxygen production due to flavin dissociation

Flavin mononucleotide (FMN) belongs to the group of very efficient endogenous photosensitizers producing singlet oxygen, (1)O(2), but with limited ability to be targeted. On the other hand, in genetically-encoded photosensitizers, which can be targeted by means of various tags, the efficiency of FMN...

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Detalles Bibliográficos
Autores principales: Petrenčáková, Martina, Filandr, František, Hovan, Andrej, Yassaghi, Ghazaleh, Man, Petr, Kožár, Tibor, Schwer, Marc-Simon, Jancura, Daniel, Plückthun, Andreas, Novák, Petr, Miškovský, Pavol, Bánó, Gregor, Sedlák, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058016/
https://www.ncbi.nlm.nih.gov/pubmed/32139757
http://dx.doi.org/10.1038/s41598-020-60861-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058016/
https://www.ncbi.nlm.nih.gov/pubmed/32139757
http://dx.doi.org/10.1038/s41598-020-60861-2

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