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Photoinduced damage of AsLOV2 domain is accompanied by increased singlet oxygen production due to flavin dissociation
Flavin mononucleotide (FMN) belongs to the group of very efficient endogenous photosensitizers producing singlet oxygen, (1)O(2), but with limited ability to be targeted. On the other hand, in genetically-encoded photosensitizers, which can be targeted by means of various tags, the efficiency of FMN...
Autores principales: | Petrenčáková, Martina, Filandr, František, Hovan, Andrej, Yassaghi, Ghazaleh, Man, Petr, Kožár, Tibor, Schwer, Marc-Simon, Jancura, Daniel, Plückthun, Andreas, Novák, Petr, Miškovský, Pavol, Bánó, Gregor, Sedlák, Erik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058016/ https://www.ncbi.nlm.nih.gov/pubmed/32139757 http://dx.doi.org/10.1038/s41598-020-60861-2 |
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