Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation

Tumor metastasis is a hallmark of cancer. Metastatic cancer cells often reside in distal tissues and organs in their dormant state. Mechanisms underlying the pre-metastatic niche formation are poorly understood. Here we show that in a colorectal cancer (CRC) model, primary tumors release integrin be...

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Detalles Bibliográficos
Autores principales: Ji, Qing, Zhou, Lihong, Sui, Hua, Yang, Liu, Wu, Xinnan, Song, Qing, Jia, Ru, Li, Ruixiao, Sun, Jian, Wang, Ziyuan, Liu, Ningning, Feng, Yuanyuan, Sun, Xiaoting, Cai, Gang, Feng, Yu, Cai, Jianfeng, Cao, Yihai, Cai, Guoxiang, Wang, Yan, Li, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058049/
https://www.ncbi.nlm.nih.gov/pubmed/32139701
http://dx.doi.org/10.1038/s41467-020-14869-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058049/
https://www.ncbi.nlm.nih.gov/pubmed/32139701
http://dx.doi.org/10.1038/s41467-020-14869-x

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