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Trajectory-based differential expression analysis for single-cell sequencing data

Trajectory inference has radically enhanced single-cell RNA-seq research by enabling the study of dynamic changes in gene expression. Downstream of trajectory inference, it is vital to discover genes that are (i) associated with the lineages in the trajectory, or (ii) differentially expressed betwee...

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Detalles Bibliográficos
Autores principales: Van den Berge, Koen, Roux de Bézieux, Hector, Street, Kelly, Saelens, Wouter, Cannoodt, Robrecht, Saeys, Yvan, Dudoit, Sandrine, Clement, Lieven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058077/
https://www.ncbi.nlm.nih.gov/pubmed/32139671
http://dx.doi.org/10.1038/s41467-020-14766-3