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A novel two-photon ratiometric fluorescent probe for imaging and sensing of BACE1 in different regions of AD mouse brain

β-Secretase (BACE1) is the vital enzyme in the pathogenic processes of Alzheimer's disease (AD). However, the development of a powerful tool with high selectivity and sensitivity for BACE1 determination in vivo is a challenge in understanding the pathogenesis of AD. In this work, a novel two-ph...

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Detalles Bibliográficos
Autores principales: Ge, Lihong, Liu, Zhichao, Tian, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058092/
https://www.ncbi.nlm.nih.gov/pubmed/32180930
http://dx.doi.org/10.1039/c9sc05256a