Domain-invariant features for mechanism of action prediction in a multi-cell-line drug screen

MOTIVATION: High-content screening is an important tool in drug discovery and characterization. Often, high-content drug screens are performed on one single-cell line. Yet, a single-cell line cannot be thought of as a perfect disease model. Many diseases feature an important molecular heterogeneity....

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Detalles Bibliográficos
Autores principales: Boyd, Joseph C, Pinheiro, Alice, Del Nery, Elaine, Reyal, Fabien, Walter, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058179/
https://www.ncbi.nlm.nih.gov/pubmed/31608933
http://dx.doi.org/10.1093/bioinformatics/btz774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058179/
https://www.ncbi.nlm.nih.gov/pubmed/31608933
http://dx.doi.org/10.1093/bioinformatics/btz774

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