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Domain-invariant features for mechanism of action prediction in a multi-cell-line drug screen
MOTIVATION: High-content screening is an important tool in drug discovery and characterization. Often, high-content drug screens are performed on one single-cell line. Yet, a single-cell line cannot be thought of as a perfect disease model. Many diseases feature an important molecular heterogeneity....
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058179/ https://www.ncbi.nlm.nih.gov/pubmed/31608933 http://dx.doi.org/10.1093/bioinformatics/btz774 |