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Proof of concept and feasibility studies examining the influence of combination ribose, adenine and allopurinol treatment on stroke outcome in the rat

BACKGROUND: Cerebral ischaemia results in a rapid and profound depletion of adenosine triphosphate (ATP), the energy currency of the cell. This depletion leads to disruption of cellular homeostasis and cell death. Early replenishment of ATP levels might therefore have a neuroprotective effect in the...

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Detalles Bibliográficos
Autores principales: Faller, Kiterie M.E., Leach, Joshua, Johnston, Pamela, Holmes, William M., Macrae, I. Mhairi, Frenguelli, Bruno G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058219/
https://www.ncbi.nlm.nih.gov/pubmed/32166133
http://dx.doi.org/10.1177/2398212817717112