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Proof of concept and feasibility studies examining the influence of combination ribose, adenine and allopurinol treatment on stroke outcome in the rat
BACKGROUND: Cerebral ischaemia results in a rapid and profound depletion of adenosine triphosphate (ATP), the energy currency of the cell. This depletion leads to disruption of cellular homeostasis and cell death. Early replenishment of ATP levels might therefore have a neuroprotective effect in the...
Autores principales: | Faller, Kiterie M.E., Leach, Joshua, Johnston, Pamela, Holmes, William M., Macrae, I. Mhairi, Frenguelli, Bruno G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058219/ https://www.ncbi.nlm.nih.gov/pubmed/32166133 http://dx.doi.org/10.1177/2398212817717112 |
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