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Hyperglycaemia does not increase perfusion deficits after focal cerebral ischaemia in male Wistar rats

BACKGROUND: Hyperglycaemia is associated with a worse outcome in acute ischaemic stroke patients; yet the pathophysiological mechanisms of hyperglycaemia-induced damage are poorly understood. We hypothesised that hyperglycaemia at the time of stroke onset exacerbates ischaemic brain damage by increa...

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Detalles Bibliográficos
Autores principales: Thow, Lisa A., MacDonald, Kathleen, Holmes, William M., Muir, Keith W., Macrae, I. Mhairi, Dewar, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058243/
https://www.ncbi.nlm.nih.gov/pubmed/32166145
http://dx.doi.org/10.1177/2398212818794820