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Differentiation of human colon tissue in culture: Effects of calcium on trans-epithelial electrical resistance and tissue cohesive properties

BACKGROUND AND AIMS: Human colonoid cultures maintained under low-calcium (0.25 mM) conditions undergo differentiation spontaneously and, concomitantly, express a high level of tight junction proteins, but not desmosomal proteins. When calcium is included to a final concentration of 1.5–3.0 mM (prov...

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Detalles Bibliográficos
Autores principales: McClintock, Shannon D., Attili, Durga, Dame, Michael K., Richter, Aliah, Silvestri, Sabrina S., Berner, Maliha M., Bohm, Margaret S., Karpoff, Kateryna, McCarthy, Caroline L., Spence, Jason R., Varani, James, Aslam, Muhammad N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058309/
https://www.ncbi.nlm.nih.gov/pubmed/32134920
http://dx.doi.org/10.1371/journal.pone.0222058