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Analysis of a large single institution cohort of related donors fails to detect a relation between SDF1/CXCR4 or VCAM/VLA4 genetic polymorphisms and the level of hematopoietic progenitor cell mobilization in response to G-CSF

We studied a cohort of 367 healthy related donors who volunteered to donate their hematopoietic stem cells for allogeneic transplantation. All donors were homogeneously cared for at a single institution, and received rhG-CSF as a mobilization treatment prior to undergoing apheresis. Peripheral blood...

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Detalles Bibliográficos
Autores principales: Garciaz, Sylvain, Sfumato, Patrick, Granata, Angela, Imbert, Anne-Marie, Fournel, Claire, Calmels, Boris, Lemarie, Claude, Chiaroni, Jacques, Blaise, Didier, Boher, Jean-Marie, Picard, Christophe, Chabannon, Christian, di Cristofaro, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058310/
https://www.ncbi.nlm.nih.gov/pubmed/32134938
http://dx.doi.org/10.1371/journal.pone.0228878