DMSO-mediated curing of several yeast prion variants involves Hsp104 expression and protein solubilization, and is decreased in several autophagy related gene (atg) mutants

Chaperones and autophagy are components of the protein quality control system that contribute to the management of proteins that are misfolded and aggregated. Here, we use yeast prions, which are self-perpetuating aggregating proteins, as a means to understand how these protein quality control syste...

Descripción completa

Detalles Bibliográficos
Autores principales: Dorweiler, Jane E., Obaoye, Joanna O., Oddo, Mitch J., Shilati, Francesca M., Scheidemantle, Grace M., Coleman, Thomas J., Reilly, Jacob A., Smith, Gregory R., Manogaran, Anita L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058316/
https://www.ncbi.nlm.nih.gov/pubmed/32134970
http://dx.doi.org/10.1371/journal.pone.0229796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058316/
https://www.ncbi.nlm.nih.gov/pubmed/32134970
http://dx.doi.org/10.1371/journal.pone.0229796

Ejemplares similares