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Methylation of SRD5A2 promoter predicts a better outcome for castration-resistant prostate cancer patients undergoing androgen deprivation therapy

PURPOSE: To determine whether SRD5A2 promoter methylation is associated with cancer progression during androgen deprivation therapy (ADT) in CRPC. PATIENTS AND METHODS: In a Local CRPC cohort, 42 prostatic specimens were collected from patients who were diagnosed as CRPC and underwent transurethral...

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Detalles Bibliográficos
Autores principales: Wang, Zongwei, Deng, Tuo, Long, Xingbo, Lin, Xueming, Wu, Shulin, Wang, Hongbo, Ge, Rongbin, Zhang, Zhenwei, Wu, Chin-Lee, Taplin, Mary-Ellen, Olumi, Aria F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058338/
https://www.ncbi.nlm.nih.gov/pubmed/32134978
http://dx.doi.org/10.1371/journal.pone.0229754