Proteasomal inhibition triggers viral oncoprotein degradation via autophagy-lysosomal pathway

Epstein-Barr virus (EBV) nuclear oncoprotein EBNA3C is essential for B-cell transformation and development of several B-cell lymphomas particularly those are generated in an immuno-compromised background. EBNA3C recruits ubiquitin-proteasome machinery for deregulating multiple cellular oncoproteins...

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Detalles Bibliográficos
Autores principales: Gain, Chandrima, Malik, Samaresh, Bhattacharjee, Shaoni, Ghosh, Arijit, Robertson, Erle S., Das, Benu Brata, Saha, Abhik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058366/
https://www.ncbi.nlm.nih.gov/pubmed/32092124
http://dx.doi.org/10.1371/journal.ppat.1008105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058366/
https://www.ncbi.nlm.nih.gov/pubmed/32092124
http://dx.doi.org/10.1371/journal.ppat.1008105

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