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On Peptides and Altered Peptide Ligands: From Origin, Mode of Action and Design to Clinical Application (Immunotherapy)

T lymphocytes equipped with clonotypic T cell antigen receptors (TCR) recognize immunogenic peptides only when presented in the context of their own major histocompatibility complex (MHC) molecules. Peptide loading to MHC molecules occurs in intracellular compartments (ER for class I and MIIC for cl...

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Detalles Bibliográficos
Autores principales: Candia, Martín, Kratzer, Bernhard, Pickl, Winfried F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058415/
https://www.ncbi.nlm.nih.gov/pubmed/27642756
http://dx.doi.org/10.1159/000448756