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Endogenous Wnt/β-catenin signaling in Müller cells protects retinal ganglion cells from excitotoxic damage

PURPOSE: To analyze whether activation of endogenous wingless (Wnt)/β-catenin signaling in Müller cells is involved in protection of retinal ganglion cells (RGCs) following excitotoxic damage. METHODS: Transgenic mice with a tamoxifen-dependent β-catenin deficiency in Müller cells were injected with...

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Detalles Bibliográficos
Autores principales: Boesl, Fabian, Drexler, Konstantin, Müller, Birgit, Seitz, Roswitha, Weber, Gregor R., Priglinger, Siegfried G., Fuchshofer, Rudolf, Tamm, Ernst R., Ohlmann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058433/
https://www.ncbi.nlm.nih.gov/pubmed/32180679