A novel architecture for achieving high drug loading in amorphous spray dried dispersion tablets

Although Amorphous Solid Dispersions (ASDs) effectively increase bioavailability, tablet mass can be high due to the large fraction of excipients needed to stabilize the amorphous drug in the solid state, extend drug supersaturation in solution and achieve robust manufacturability. The aim of this w...

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Detalles Bibliográficos
Autores principales: Mudie, Deanna M., Buchanan, Stephanie, Stewart, Aaron M., Smith, Adam, Shepard, Kimberly B., Biswas, Nishant, Marshall, Derrick, Ekdahl, Alyssa, Pluntze, Amanda, Craig, Christopher D., Morgen, Michael M., Baumann, John M., Vodak, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058468/
https://www.ncbi.nlm.nih.gov/pubmed/32154509
http://dx.doi.org/10.1016/j.ijpx.2020.100042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058468/
https://www.ncbi.nlm.nih.gov/pubmed/32154509
http://dx.doi.org/10.1016/j.ijpx.2020.100042

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