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miR-125a Induces HER2 Expression and Sensitivity to Trastuzumab in Triple-Negative Breast Cancer Lines

The EGFR/HER2 signaling network is an effective therapeutic target for HER2-positive cancers, which are known for their aggressive biological course. Evidence indicates that the EGFR/HER2 network plays a role in the aggressive basal-like subtype as well. Here, we studied the potential role of miR-12...

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Detalles Bibliográficos
Autores principales: Ninio-Many, Lihi, Hikri, Elad, Burg-Golani, Tamar, Stemmer, Salomon M., Shalgi, Ruth, Ben-Aharon, Irit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058585/
https://www.ncbi.nlm.nih.gov/pubmed/32185126
http://dx.doi.org/10.3389/fonc.2020.00191