Porcine Circovirus Type 2 ORF5 Protein Induces Autophagy to Promote Viral Replication via the PERK-eIF2α-ATF4 and mTOR-ERK1/2-AMPK Signaling Pathways in PK-15 Cells

Porcine circovirus type 2 (PCV2) is the primary causative agent that causing porcine circovirus-associated disease (PCVAD). The open reading frame 5 (ORF5) protein is a newly discovered non-structural protein in PCV2, which the function in viral pathogenesis remains unknown. The aim of this study wa...

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Detalles Bibliográficos
Autores principales: Lv, Jiangman, Jiang, Yanfen, Feng, Quanwen, Fan, Zhixin, Sun, Ying, Xu, Panpan, Hou, Yufeng, Zhang, Xiuping, Fan, Yuxin, Xu, Xingang, Zhang, Yanming, Guo, Kangkang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058596/
https://www.ncbi.nlm.nih.gov/pubmed/32184774
http://dx.doi.org/10.3389/fmicb.2020.00320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058596/
https://www.ncbi.nlm.nih.gov/pubmed/32184774
http://dx.doi.org/10.3389/fmicb.2020.00320

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