miR-221 and -222 target CACNA1C and KCNJ5 leading to altered cardiac ion channel expression and current density

MicroRNAs (miRs) contribute to different aspects of cardiovascular pathology, among others cardiac hypertrophy and atrial fibrillation. The aim of our study was to evaluate the impact of miR-221/222 on cardiac electrical remodeling. Cardiac miR expression was analyzed in a mouse model with altered e...

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Detalles Bibliográficos
Autores principales: Binas, Stephanie, Knyrim, Maria, Hupfeld, Julia, Kloeckner, Udo, Rabe, Sindy, Mildenberger, Sigrid, Quarch, Katja, Strätz, Nicole, Misiak, Danny, Gekle, Michael, Grossmann, Claudia, Schreier, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058603/
https://www.ncbi.nlm.nih.gov/pubmed/31312877
http://dx.doi.org/10.1007/s00018-019-03217-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058603/
https://www.ncbi.nlm.nih.gov/pubmed/31312877
http://dx.doi.org/10.1007/s00018-019-03217-y

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